Publications

 

2019

Endothelial tip cells in vitro are less glycolytic and have a more flexible response to metabolic stress than non-tip cells.
Scientific Reports 9, Article number: 10414

Anti-angiogenic effects of crenolanib are mediated by mitotic modulation independently of PDGFR expression.
Br. J. Cancer 121, 139–149

Expression patterns of endothelial permeability pathways in the development of the blood-retinal barrier in mice.
FASEB J. 2019 Jan 30

2018

The role of plasmalemma vesicle-associated protein in pathological breakdown of blood–brain and blood–retinal barriers: potential novel therapeutic target for cerebral edema and diabetic macular edema.
Fluids and Barriers of the CNS (2018) 15:24

Glucocorticoids exert differential effects on the endothelium in an in vitro model of the blood-retinal barrier.
Acta Ophthalmol. 2018 Aug 31.[ahead of print]

IGF2 and IGF1R identified as novel tip cell genes in primary microvascular endothelial cell monolayers
Angiogenesis [ahead of print]

Consensus guidelines for the use and interpretation of angiogenesis assays.
Angiogenesis. 2018 May 15. doi: 10.1007/s10456-018-9613-x. [Epub ahead of print]

Spatial and temporal recruitment of the neurovascular unit during development of the mouse blood-retinal barrier.
Tissue and Cell 2018; 52:42-50.

Involvement of the ubiquitin-proteasome system in the expression of extracellular matrix genes in retinal pigment epithelial cells.
Biochem Biophys Rep. 2018 Jan 28;13:83-92.

2017

Identification of proteins associated with clinical and pathological features of proliferative diabetic retinopathy in vitreous and fibrovascular membranes.
PLoS One. 2017 Nov 2;12(11):e0187304.

Modulation of the Proteasome Pathway by Nano-Curcumin and Curcumin in Retinal Pigment Epithelial Cells.
Ophthalmic Res. 2017 Oct 27.

Is leukostasis a crucial step or epiphenomenon in the pathogenesis of diabetic retinopathy?
J Leukoc Biol. 2017 Oct;102(4):993-1001.

TNFα-Induced Disruption of the Blood-Retinal Barrier In Vitro Is Regulated by Intracellular 3',5'-Cyclic Adenosine Monophosphate Levels.
Invest Ophthalmol Vis Sci. 2017 Jul 1;58(9):3496-3505.

2016

Computational Screening of Tip and Stalk Cell Behavior Proposes a Role for Apelin Signaling in Sprout Progression.
PLoS One. 2016;11:e0159478.

Association of Circulating Markers With Outcome Parameters in the Bevacizumab and Ranibizumab in Diabetic Macular Edema Trial.
Invest Ophthalmol Vis Sci. 2016;57:6234-6241.

CD34 Promotes Pathological Epi-Retinal Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy.
PLoS One. 2016; 11:e0157902.

Role of sulfatase 2 in lipoprotein metabolism and angiogenesis.
Curr Opin Lipidol. 2016;27:181-6.

Plasmalemma Vesicle Associated Protein Has a Key Role in Blood-Retinal Barrier Loss.
Am J Pathol. 2016;186:1044-54.

2015

Tip Cells in Angiogenesis
In: eLS. John Wiley & Sons Ltd, Chichester.

The role of CTGF in diabetic retinopathy.
Exp Eye Res. 2015;133:37-48.

2014

Computational Screening of Angiogenesis Model Variants Predicts that Differential Chemotaxis Helps Tip Cells Move to the Sprout Tip and Accelerates Sprouting.
arXiv:1409.5895 [q-bio.CB]

Molecular analysis of blood-retinal barrier loss in the Akimba mouse, a model of advanced diabetic retinopathy.
Exp Eye Res. 2014;122:123-31

Connective tissue growth factor is involved in structural retinal vascular changes in long-term experimental diabetes.
J Histochem Cytochem. 2014;62:109-18.

2013

Complement factor C3a alters proteasome function in human RPE cells and in an animal model of age-related RPE degeneration.
Invest Ophthalmol Vis Sci. 2013 Oct 3.

Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions. Review.
Prog Retin Eye Res. 2013 Feb 13.

Endothelial tip cells in ocular angiogenesis: potential target for anti-angiogenesis therapy. Review.
J Histochem Cytochem. 2013 Feb;61(2):101-15.

Vitreous TIMP-1 levels associate with neovascularization and TGF-β2 levels but not with fibrosis in the clinical course of proliferative diabetic retinopathy.
J Cell Commun Signal. 2013 Mar;7(1):1-9.

2012

A shift in the balance of vascular endothelial growth factor and connective tissue growth factor by bevacizumab causes the angiofibrotic switch in proliferative diabetic retinopathy.
Br J Ophthalmol. 2012 Apr;96(4):587-90.

CD34 marks angiogenic tip cells in human vascular endothelial cell cultures.
Angiogenesis. 2012 Mar;15(1):151-63.

A novel co-culture model of the blood-retinal barrier based on primary retinal endothelial cells, pericytes and astrocytes.
Exp Eye Res. 2012 Mar;96(1):181-90.

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