Book Now
Toggle navigation
Home
About
Research
Publications
Onderzoek
contact
Publications
2022
Common pathways in dementia and diabetic retinopathy: understanding the mechanisms of diabetes-related cognitive decline.
Trends Endocrinol Metab (2022) 33:50-71.
2021
miRNA Levels as a Biomarker for Anti-VEGF Response in Patients with Diabetic Macular Edema.
J Pers Med (2021) 11:1297.
PDGF as an Important Initiator for Neurite Outgrowth Associated with Fibrovascular Membranes in Proliferative Diabetic Retinopathy.
Curr Eye Res (2021) Oct 6:1-10.
Exploring the choroidal vascular labyrinth and its molecular and structural roles in health and disease.
Prog Retin Eye Res (2021) Jul 17:100994.
The Role of Heparan Sulfate and Neuropilin 2 in VEGFA Signaling in Human Endothelial Tip Cells and Non-Tip Cells during Angiogenesis In Vitro.
Cells (2021) 10:926
Angiogenesis in gynecological cancers and the options for anti-angiogenesis therapy.
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer (2021) 1875:188446
2020
microRNA Expression Profile in the Vitreous of Proliferative Diabetic Retinopathy Patients and Differences from Patients Treated with Anti-VEGF Therapy.
Trans Vis Sci Tech (2020) 9:16
IGF-binding proteins 3 and 4 are regulators of sprouting angiogenesis.
Mol Biol Rep (2020) 47:2561-2572
2019
The role of glycolysis and mitochondrial respiration in the formation and functioning of endothelial tip cells during angiogenesis.
Scientific Reports (2019) 9:12608
Endothelial tip cells in vitro are less glycolytic and have a more flexible response to metabolic stress than non-tip cells.
Scientific Reports (2019) 9:10414
Anti-angiogenic effects of crenolanib are mediated by mitotic modulation independently of PDGFR expression.
Br. J. Cancer (2019) 121:139–149
Expression patterns of endothelial permeability pathways in the development of the blood-retinal barrier in mice.
FASEB J. (2019) 33:5320-5333
Glucocorticoids exert differential effects on the endothelium in an in vitro model of the blood-retinal barrier.
Acta Ophthalmol (2019) 97:214-224.
2018
The role of plasmalemma vesicle-associated protein in pathological breakdown of blood–brain and blood–retinal barriers: potential novel therapeutic target for cerebral edema and diabetic macular edema.
Fluids and Barriers of the CNS (2018) 15:24.
IGF2 and IGF1R identified as novel tip cell genes in primary microvascular endothelial cell monolayers
Angiogenesis (2018) 1:823-836
Consensus guidelines for the use and interpretation of angiogenesis assays.
Angiogenesis (2018) 21:425-532.
Spatial and temporal recruitment of the neurovascular unit during development of the mouse blood-retinal barrier.
Tissue and Cell (2018) 52:42-50.
Involvement of the ubiquitin-proteasome system in the expression of extracellular matrix genes in retinal pigment epithelial cells.
Biochem Biophys Rep (2018)13:83-92.
2017
Identification of proteins associated with clinical and pathological features of proliferative diabetic retinopathy in vitreous and fibrovascular membranes.
PLoS One (2017) 12:e0187304.
Modulation of the Proteasome Pathway by Nano-Curcumin and Curcumin in Retinal Pigment Epithelial Cells.
Ophthalmic Res (2017) 59:98-109.
Is leukostasis a crucial step or epiphenomenon in the pathogenesis of diabetic retinopathy?
J Leukoc Biol (2017) 102:993-1001.
TNFα-Induced Disruption of the Blood-Retinal Barrier In Vitro Is Regulated by Intracellular 3',5'-Cyclic Adenosine Monophosphate Levels.
Invest Ophthalmol Vis Sci (2017) 58:3496-3505.
2016
Computational Screening of Tip and Stalk Cell Behavior Proposes a Role for Apelin Signaling in Sprout Progression.
PLoS One (2016) 11:e0159478.
Association of Circulating Markers With Outcome Parameters in the Bevacizumab and Ranibizumab in Diabetic Macular Edema Trial.
Invest Ophthalmol Vis Sci (2016) 57:6234-6241.
CD34 Promotes Pathological Epi-Retinal Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy.
PLoS One (2016) 11:e0157902.
Role of sulfatase 2 in lipoprotein metabolism and angiogenesis.
Curr Opin Lipidol (2016) 27:181-6.
Plasmalemma Vesicle Associated Protein Has a Key Role in Blood-Retinal Barrier Loss.
Am J Pathol (2016) 186:1044-54.
2015
Tip Cells in Angiogenesis
In: eLS. John Wiley & Sons Ltd, Chichester.
The role of CTGF in diabetic retinopathy.
Exp Eye Res (2015) 133:37-48.
2014
Computational Screening of Angiogenesis Model Variants Predicts that Differential Chemotaxis Helps Tip Cells Move to the Sprout Tip and Accelerates Sprouting.
arXiv:1409.5895 [q-bio.CB]
Molecular analysis of blood-retinal barrier loss in the Akimba mouse, a model of advanced diabetic retinopathy.
Exp Eye Res (2014)122:123-31
Connective tissue growth factor is involved in structural retinal vascular changes in long-term experimental diabetes.
J Histochem Cytochem (2014) 62:109-18.
2013
Complement factor C3a alters proteasome function in human RPE cells and in an animal model of age-related RPE degeneration.
Invest Ophthalmol Vis Sci (2013) 54:6489-501.
Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions. Review.
Prog Retin Eye Res (2013) 34:19-48.
Endothelial tip cells in ocular angiogenesis: potential target for anti-angiogenesis therapy. Review.
J Histochem Cytochem (2013) 61:101-15.
Vitreous TIMP-1 levels associate with neovascularization and TGF-β2 levels but not with fibrosis in the clinical course of proliferative diabetic retinopathy.
J Cell Commun Signal (2013) 7:1-9.
2012
A shift in the balance of vascular endothelial growth factor and connective tissue growth factor by bevacizumab causes the angiofibrotic switch in proliferative diabetic retinopathy.
Br J Ophthalmol (2012) 96:587-90.
CD34 marks angiogenic tip cells in human vascular endothelial cell cultures.
Angiogenesis (2012) 15:151-63.
A novel co-culture model of the blood-retinal barrier based on primary retinal endothelial cells, pericytes and astrocytes.
Exp Eye Res (2012) 96:181-90.
more publications
Top